Common Hypertension Drugs Can Raise Blood Pressure in Certain Patients
• Severe Hypertension News • Aug 19 10
Commonly prescribed drugs used to lower blood pressure can actually have the opposite effect??”raising blood pressure in a statistically significant percentage of patients. A new study by researchers at Albert Einstein College of Medicine of Yeshiva University suggests that doctors could avoid this problem??”and select drugs most suitable for their patients??”by measuring blood levels of the enzyme renin through a blood test that is becoming more widely available. The study appears in the online edition of the American Journal of Hypertension.

???Our findings suggest that physicians should use renin levels to predict the most appropriate first drug for treating patients with hypertension,??? says lead author Michael Alderman, M.D., professor of epidemiology & population health and of medicine at Einstein. ???This would increase the likelihood of achieving blood pressure control and reduce the need for patients to take additional antihypertensive medications.???

The study involved 945 patients who were enrolled in a workplace antihypertensive treatment program in New York City from 1981 to 1998.     

Blood pressure test may help guide treatment
• Severe Hypertension News • Aug 19 10
Tests for a blood-pressure regulating hormone called renin may help doctors decide which blood pressure drugs their patients should take, researchers said on Wednesday.…    

Expensive new blood pressure meds no better than generics
• Severe Hypertension News • Aug 13 10
Expensive brand-name medications to lower blood pressure are no better at preventing cardiovascular disease than older, generic diuretics, according to new long-term data from…    

SORTing Out the Links Between Cholesterol and Coronary Heart Disease
• Severe Hypertension News • Aug 05 10
The true power of genomic research lies in its ability to help scientists understand biological processes, particularly those that ??“ when altered ??“ can lead to disease. This power is demonstrated dramatically in a pair of papers published today in the journal Nature. In the first, a global team of researchers describes 95 different variations across the genome that contribute in different degrees to alterations in blood cholesterol and triglyceride levels in multiple human populations. In the second report, close examination of just one of these common variants not only reveals the involvement of an unexpected genetic pathway in lipid metabolism but also provides a blueprint for using genomic findings to unravel biological connections between lipid levels and coronary heart disease.

???Although blood concentrations of cholesterol and triglycerides have long been known as risk factors for cardiovascular disease, the extent to which genetics contributes to those concentrations and just how alterations in the underlying genes leads to the development of disease has been incredibly difficult to piece together,??? said Dr. Sekar Kathiresan, director of Preventive Cardiology at Massachusetts General Hospital (MGH), an associate member of the Broad Institute of Harvard and MIT, and co-senior author on both papers. ???In these two papers, we provide 95 signposts indicating genes that contribute to plasma lipid concentrations. In addition, we delve deeper into one specific signpost and move from genomic localization to biologic understanding by discovering how genetic variation leads to clinical symptoms in living organisms. We believe our approach is a model for many other such studies across multiple diseases.???    

For blood pressure, can you be fit but fat?
• Severe Hypertension News • Jul 30 10
If you’re trying to bring your blood pressure to healthy levels, a new study suggests that how much you weigh is more important…    

Ben-Gurion University of the Negev researchers identify risks of hypertension in young adults
• Severe Hypertension News • Jul 27 10
Ben-Gurion University of the Negev (BGU) researchers reveal in a new, large-scale study that “normal” blood pressure at age 17 can still predict hypertension…    

Are blood pressure goals for diabetics too tough?
• Severe Hypertension News • Jul 07 10
Aggressively controlling blood pressure in diabetics with heart disease may do little to reduce their risks of dying early and may even be dangerous,…    

High Fructose Diet May Contribute to High Blood Pressure
• Severe Hypertension News • Jul 06 10
People who eat a diet high in fructose, in the form of added sugar, are at increased risk of developing high blood pressure, or hypertension, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results suggest that cutting back on foods and beverages containing a lot of fructose (sugar) might decrease one??™s risk of developing hypertension.

Hypertension is the most common chronic condition in developed countries and a major risk factor for heart and kidney diseases. Researchers are striving to identify environmental factors that might be responsible for the development of hypertension, and they suspect that fructose may play a role. Over the past century, a dramatic increase in the consumption of this simple sugar, which is used to sweeten a wide variety of processed foods, mirrors the dramatic rise in the prevalence of hypertension.

To examine whether increased fructose consumption has contributed to rising rates of hypertension, Diana Jalal, MD (University of Colorado Denver Health Sciences Center) and her colleagues analyzed data from the National Health and Nutrition Examination Survey (2003-2006).     

Too much fructose could raise your blood pressure
• Severe Hypertension News • Jul 02 10
Do you need a reason to cut down on sweetened beverages? Their fructose content might increase your blood pressure, doctors said Thursday.

…    

Benicar reduces blood pressure in hypertension, diabetes patients
• Severe Hypertension News • Jun 30 10
An investigational treatment made by Daiichi Sankyo for hypertension significantly lowers blood pressure in patients with hard-to-treat hypertension and diabetes, according to results of…    

Dark chocolate lowers blood pressure
• Severe Hypertension News • Jun 28 10
For people with hypertension, eating dark chocolate can significantly reduce blood pressure. Researchers writing in the open access journal BMC Medicine combined the results of 15 studies into the effects of flavanols, the compounds in chocolate which cause dilation of blood vessels, on blood pressure.

Dr Karin Ried worked with a team of researchers from the University of Adelaide, Australia, to conduct the analysis. She said, “Flavanols have been shown to increase the formation of endothelial nitric oxide, which promotes vasodilation and consequently may lower blood pressure. There have, however, been conflicting results as to the real-life effects of eating chocolate. We’ve found that consumption can significantly, albeit modestly, reduce blood pressure for people with high blood pressure but not for people with normal blood pressure”.

The pressure reduction seen in the combined results for people with hypertension, 5mm Hg systolic, may be clinically relevant ??“ it is comparable to the known effects of 30 daily minutes of physical activity (4-9mm Hg) and could theoretically reduce the risk of a cardiovascular event by about 20% over five years.    

EU regulators probe risks of blood pressure drugs
• Severe Hypertension News • Jun 26 10
European drugs regulators have launched an investigation into the possible increased risk of cancer in patients taking common blood pressure medicines known as angiotensin-receptor…    

Water leaf, alligator pepper treats hypertension - survey
• Severe Hypertension News • Jun 24 10
The contribution of indigenous knowledge using plants to provide native remedies for varieties of ailment has been a fulcrum many African scientists rely on…    

Combination therapy in hypertension: an update
• Severe Hypertension News • Jun 24 10
Meticulous control of blood pressure is required in patients with hypertension to produce the maximum reduction in clinical cardiovascular end points, especially in patients…    

Newer devices often underestimate blood pressure
• Severe Hypertension News • Jun 22 10
Automated blood pressure measuring devices are replacing old-fashioned mercury manometers in doctor’s offices and clinics around the world. But a new head-to-head comparison of…    

Updating Hypertension and Cholesterol Guidelines
• Severe Hypertension News • Jun 17 10
Updating Hypertension and Cholesterol Guidelines: An Expert Interview With Joseph Saseen, PharmD, FCCP, BCPS

Editor’s note: The management of hypertension and dyslipidemia…    

Independent Study Reveals dabl System Leads the way in Accurate Cardiovascular Diagnosis
• Severe Hypertension News • Jun 17 10
An independent study has revealed that Irish Company, dabl’s computerised system for diagnosing 24 hour blood pressure is more accurate and consistent than a…    

Hypertension drugs linked to cancer
• Severe Hypertension News • Jun 17 10
Results from a meta-analysis show patients treated with angiotensin-receptor blockers (ARBs) have an increased risk of developing a cancer.

The analysis published…    

Risk factors and warning signs of stroke
• Severe Hypertension News • Jun 16 10
A stroke can happen anytime, anywhere and to anyone, regardless of age, gender or ethnicity. However, there are risk factors and warning signs to be aware of to combat stroke and increase a victim??™s survival rate.

???A stroke occurs when a blood clot blocks an artery or a blood vessel breaks, interrupting blood flow to an area of the brain,??? says Carmen T. Ramirez, M.D., clinical assistant professor at the Texas A&M Health Science Center College of Medicine. ???When either of these things happens, brain cells begin to die, and brain damage occurs.???

Two types of risk factors predispose you to stroke: modifiable and fixed. Modifiable factors ??“ those that can be changed with healthy lifestyle choices ??“ include hypertension and high cholesterol, diabetes, diet and activity, and tobacco use.    

High Blood Pressure Risk Looms for Teen Boys
• Severe Hypertension News • Jun 16 10
Adolescent boys with normal blood pressure are three to four times more likely than girls to develop high blood pressure, a large study has…    

Battling Hypertension in the Community
• Severe Hypertension News • Jun 16 10
Health and business organizations are joining forces in the battle against hypertension. The Rochester Business Alliance and the Finger Lakes Health Systems Agency are…    

Pine Nut Oil.org Natural Remedy for Arterial Hypertension
• Severe Hypertension News • Jun 15 10
Pine Nut Oil.org released clinical study of effectiveness of using pine nut oil in the comprehensive treatment of patients with arterial hypertension

In patients with arterial hypertension who are receiving basic hypertension treatment, the consumption of a 17.5 g daily dose of Siberian Pine Nut Oil demonstrated a cholesterol lowering effect, was accompanied by the normalization of the lipid spectrum of the blood and systolic pressure, and a decrease in excess body mass.

The prime objective in treating patients with arterial hypertension is to lower patients??™ elevated blood pressure and thereby reduce the risk of the onset of cardiovascular complications that occur, as is well known, on the background of an elevated level of cholesterol in the blood and general obesity.     

Hypertension drug cancer scare: don’t rethink ARBs yet
• Severe Hypertension News • Jun 15 10
Angiotensin Receptor Blockers (ARBs) have become one of our most popular hypertension drugs in recent years.

And now they??™re facing a cancer scare.

A new study in the British journal Lancet Oncology conducted by Case Western in Cleveland shows a small but ???statistically significant??? rise in cancer cases, 1.2%, among patients taking ARBs.    

Common blood pressure drugs may raise cancer risk
• Severe Hypertension News • Jun 14 10
A widely used class of blood pressure drugs may slightly increase the risk of cancer, U.S. researchers said on Sunday, and they are calling…    

Hypertension: Competing Treatments and Market Entry Considerations for the Market
• Severe Hypertension News • Jun 12 10
Hypertension: Competing Treatments and Market Entry Considerations for the Market Expected to Reach 1.5 Billion People in 2025

Research and Markets has…    

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