The Effect of the Kidney on Blood Pressure
Monday, Dec 10 2007
The kidneys are organs that are ultimately responsible for the amount of fluid the body retains, and thus exert a significant effect on regulating blood volume and blood pressure.
Increased blood pressure detected by the kidneys results in increased urinary excretion, and reductions in blood pressure result in lowered excretion rates, both regulating blood pressure by altering blood volume.
During the bout of exercise, however, a portion of the blood volume is absorbed into muscle and skin cells and fluid excreted via sweat glands, rather than the kidneys alone regulating body fluid.
As stated above, the kidneys also affect blood pressure through release of renin. Essentially, when the kidneys detect a drop in blood pressure, renin is released, leading to increased vasoconstriction and sodium retention that elevate blood pressure to its previous level. This renin-angiotensin-aldosterone system, then, represents an important feedback system involved in blood pressure regulation.
Polefrone, J. M., Manuck, S. B., Larkin, K. T., and Francis, M. E.
Published with assistance from the foundation established in memory of Amasa Stone Mather of the Class of 1907, Yale College.
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Last revised: by Dr. Karen Severson, Ph.D.
Provided by Armina Hypertension Association
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